abstract：:Multiple sclerosis is thought, by many investigators, to be an immunologic disease. Therefore, a rationale exists for treating this disease by immunosuppressive therapy. In exacerbating-remitting multiple sclerosis, corticosteroids and adrenocorticotropic hormone are the most widely used drugs; high doses of intraveno...

journal_title：Mayo Clinic proceedings

authors： Carter JL,Rodriguez M

更新日期：1989-06-01 00:00:00

abstract：:The first 100 liver transplantations at the Mayo Clinic were performed in 83 patients, who required a total of 917 patient days in the intensive-care unit (ICU). The mean duration of stay in the ICU was 5.91 days after liver transplantation and 6.15 days for patients who subsequently required readmission to the ICU. D...

journal_title：Mayo Clinic proceedings

authors： Plevak DJ,Southorn PA,Narr BJ,Peters SG

更新日期：1989-04-01 00:00:00

abstract：:In a prospective study of 10 patients who underwent liver transplantation and 10 patients who underwent cholecystectomy, we analyzed the postoperative analgesic requirements and the resultant plasma morphine concentrations. Analgesia was more intense, with less medication, and the plasma morphine concentration was sig...

journal_title：Mayo Clinic proceedings

authors： Eisenach JC,Plevak DJ,Van Dyke RA,Southorn PA,Danielson DR,Krom RA,Nagorney DM,Rettke SR

更新日期：1989-03-01 00:00:00

abstract：:Anesthesia support for patients undergoing orthotopic liver transplantation can be complicated because of multiple medical problems in such patients and rapid hemodynamic, metabolic, and coagulation changes intraoperatively. Preoperative assessment should include careful review of the cardiovascular, respiratory, and ...

journal_title：Mayo Clinic proceedings

authors： Rettke SR,Chantigian RC,Janossy TA,Burritt MF,Van Dyke RA,Harper JV,Ilstrup DM,Taswell HF,Wiesner RH,Krom RA

更新日期：1989-02-01 00:00:00

abstract：:Many patients taking customary doses of levothyroxine have slightly elevated serum thyroxine (T4), apparently normal serum triiodothyronine, suppressed serum thyrotropin (thyroid-stimulating hormone; TSH) concentrations, and no clinical symptoms of hyperthyroidism. Recent reports suggest that these patients may have a...

journal_title：Mayo Clinic proceedings

authors： Ross DS

更新日期：1988-12-01 00:00:00

abstract：:Lyme disease is a multisystem disorder caused by a tick-transmitted spirochete, Borrelia burgdorferi. The diagnosis is based on clinical findings in most patients, particularly those with erythema migrans or exposure to geographic locations endemic for the disease. Detection of a specific antibody to B. burgdorferi is...

journal_title：Mayo Clinic proceedings

authors： Duffy J,Mertz LE,Wobig GH,Katzmann JA

更新日期：1988-11-01 00:00:00

abstract：:Pergolide is a potent dopamine agonist and is known to have anti-Parkinson properties. We administered pergolide to patients with suboptimal control of Parkinson's disease who had a short-duration response to carbidopa-levodopa in a 6-month, double-blind study. Pergolide added to the carbidopa-levodopa regimen resulte...

journal_title：Mayo Clinic proceedings

authors： Ahlskog JE,Muenter MD

更新日期：1988-10-01 00:00:00

abstract：:Lipoproteins are known to be able to transport a variety of drugs. This report suggests that low-density lipoprotein not only functions as an important carrier of cyclosporine in plasma but also facilitates transport of cyclosporine across the cell membrane by means of the low-density lipoprotein receptor. Such a mech...

journal_title：Mayo Clinic proceedings

authors： de Groen PC

更新日期：1988-10-01 00:00:00

abstract：:Multiple regression analysis were used to investigate the relationship between blood pressure and age, sex, relative weight, antihypertensive medication, diabetes mellitus, diet (low-salt, low-cholesterol, and weight-reducing regimens), cigarette smoking, coffee drinking, and aerobic exercise among a stratified random...

journal_title：Mayo Clinic proceedings

authors： Phillips SJ,O'Fallon WM,Whisnant JP

更新日期：1988-07-01 00:00:00

abstract：:The introduction of transesophageal echocardiography has provided a new acoustic window to the heart and mediastinum. High-quality images of certain cardiovascular structures [left atrial appendage, thoracic aorta, mitral valvular apparatus, and atrial septum] can be obtained readily (average examination, 15 to 20 min...

journal_title：Mayo Clinic proceedings

authors： Seward JB,Khandheria BK,Oh JK,Abel MD,Hughes RW Jr,Edwards WD,Nichols BA,Freeman WK,Tajik AJ

更新日期：1988-07-01 00:00:00

abstract：:In 51 patients who had 20 different models of permanent cardiac pacemakers, we conducted transcutaneous electrical nerve stimulation studies at four anatomic sites--the lumbar area, cervical spine, left leg, and lower arm area ipsilateral to the pacemaker. With a mean stimulation of 24.7 Hz, no episodes of interferenc...

journal_title：Mayo Clinic proceedings

authors： Rasmussen MJ,Hayes DL,Vlietstra RE,Thorsteinsson G

更新日期：1988-05-01 00:00:00

abstract：:Chest pain in a young person is often caused by chest wall tenderness, associated with mitral valve prolapse, or attributed to psychologic factors. Ischemic cardiac pain may be overlooked because of its rare occurrence in this age group. A 35-year-old woman complained of substernal chest pressure precipitated by exert...

journal_title：Mayo Clinic proceedings

authors： Click RL,Spittell JA Jr,Puga FJ

更新日期：1988-04-01 00:00:00

abstract：:We describe a patient who had severe myalgias, bronchial asthma, pulmonary infiltrates, and eosinophilia. The findings on physical examination and the erythrocyte sedimentation rate were normal; there was no elevation of the serum creatine kinase. Muscle biopsy demonstrated an inflammatory exudate that contained eosin...

journal_title：Mayo Clinic proceedings

authors： Lakhanpal S,Duffy J,Engel AG

更新日期：1988-01-01 00:00:00

abstract：:Thirty-five patients with a diagnosis of pure ovarian dysgerminoma underwent assessment at our institution between 1950 and 1984. The median age of these patients was 21 years (range, 8 to 41 years). The surgical pathologic stages of the tumors were as follows: stage IA1 in 18 patients, stage IA2 in 2, stage IB1 in 2,...

journal_title：Mayo Clinic proceedings

authors： Buskirk SJ,Schray MF,Podratz KC,Lee RA,Stanhope CR,Gaffey TA,Weber FC,Earle JD,Naessens JM,Malkasian GD

更新日期：1987-12-01 00:00:00

abstract：:The fluoroquinolones are a new class of antimicrobial agents structurally related to nalidixic acid. They have a broad spectrum of activity against pathogens, including Pseudomonas aeruginosa, other multiresistant gram-negative bacteria, and methicillin-resistant Staphylococcus aureus but not anaerobes. They are well ...

journal_title：Mayo Clinic proceedings

authors： Walker RC,Wright AJ

更新日期：1987-11-01 00:00:00

abstract：:Aerobic exercise training has been used as part of the treatment for a variety of chronic disorders, most notably cardiovascular disease. In order to determine the feasibility and utility of regular exercise after renal transplantation, the responses of 10 patients to graded exercise testing were compared before train...

journal_title：Mayo Clinic proceedings

authors： Miller TD,Squires RW,Gau GT,Ilstrup DM,Frohnert PP,Sterioff S

更新日期：1987-09-01 00:00:00

abstract：:A 56-year-old man sought medical assistance because of recurrent nonconvulsive status epilepticus without a history of prior seizure activity. Examination of the cerebrospinal fluid disclosed leptomeningeal cancer. To our knowledge, the association of partial complex status epilepticus and leptomeningeal cancer has no...

journal_title：Mayo Clinic proceedings

authors： Broderick JP,Cascino TL

更新日期：1987-09-01 00:00:00

abstract：:Stereotactic ventralis lateralis thalamotomy can be performed in selected patients with medically intractable parkinsonian tremor and rigidity. New technology, including computed tomography-based stereotaxis and microelectrode recording techniques, provides a data base for precise localization of thalamic lesions tail...

journal_title：Mayo Clinic proceedings

authors： Kelly PJ,Ahlskog JE,Goerss SJ,Daube JR,Duffy JR,Kall BA

更新日期：1987-08-01 00:00:00

abstract：:We measured cardiopulmonary function at rest and during exercise in 15 healthy survivors of neonatal respiratory distress syndrome (RDS) and compared the results with those in 15 normal subjects. The mean birth weight of the RDS group was 1,771 g, and 12 of the 15 patients had required endotracheal intubation. The oxy...

journal_title：Mayo Clinic proceedings

authors： Driscoll DJ,Kleinberg F,Heise CT,Staats BA

更新日期：1987-08-01 00:00:00

abstract：:A retrospective review of Mayo Clinic records through 1983 revealed 84 patients (24 male and 10 female; mean age, 41 years) with the diagnosis of pulmonary alveolar phospholipoproteinosis. The major clinical features were dyspnea, cough, fever, and chest pain. Chest roentgenograms usually showed bilateral symmetric al...

journal_title：Mayo Clinic proceedings

authors： Prakash UB,Barham SS,Carpenter HA,Dines DE,Marsh HM

更新日期：1987-06-01 00:00:00

abstract：:The sensitivity of an indirect fluorescent antibody (IFA) test (screening test) for the detection of antibodies to cytomegalovirus (CMV) was examined by using 128 serum specimens and quaternary aminoethyl (QAE)-Sephadex A50 column chromatography to separate IgM from IgG class antibodies. Of these 128 rheumatoid factor...

journal_title：Mayo Clinic proceedings

authors： Elder BL,Shelley CD,Smith TF

更新日期：1987-05-01 00:00:00

abstract：:Campylobacter-like organisms (provisionally named C. pyloridis) were demonstrated in gastric biopsy specimens by histopathologic analysis and bacterial culture. C. pyloridis organisms were found in 12 of 26 patients (46%) with gastric or duodenal ulcer but in none of 10 healthy volunteers without histologic evidence o...

journal_title：Mayo Clinic proceedings

authors： Gustavsson S,Phillips SF,Malagelada JR,Rosenblatt JE

更新日期：1987-04-01 00:00:00

abstract：:Breast reconstruction immediately after mastectomy is being used with increasing frequency. In a study of the first 100 consecutive patients at our institution who underwent this procedure, with (21 patients) or without (79 patients) later nipple reconstruction, 85% responded affirmatively on a follow-up questionnaire...

journal_title：Mayo Clinic proceedings

authors： van Heerden JA,Jackson IT,Martin JK Jr,Fisher J

更新日期：1987-03-01 00:00:00

abstract：:Since the early 1970s, investigators have been interested in the relationship between dietary marine fish oils and plasma lipoproteins. Previous studies have shown that consumption of a diet rich in marine fatty acids results in altered lipid profiles, prolonged bleeding times, reduced platelet aggregation, and decrea...

journal_title：Mayo Clinic proceedings

authors： Ballard-Barbash R,Callaway CW

更新日期：1987-02-01 00:00:00

abstract：:Continuous spontaneous electromyographic activity and responses to electrical stimulation of the facial nerve in the surgical field were monitored in 48 patients undergoing primary removal of an acoustic neuroma. The operative and postoperative results in these patients were compared with the results in 48 patients wh...

journal_title：Mayo Clinic proceedings

authors： Harner SG,Daube JR,Ebersold MJ,Beatty CW

更新日期：1987-02-01 00:00:00

abstract：:Between December 1980 and April 1986 at our institution, 38 patients with cancer that involved the tracheobronchial tree (a total of 40 carcinomas) completed at least one course of hematoporphyrin derivative phototherapy. A complete response occurred in 13 patients (with 14 carcinomas). Eleven of these carcinomas did ...

journal_title：Mayo Clinic proceedings

authors： Edell ES,Cortese DA

更新日期：1987-01-01 00:00:00

abstract：:Two-dimensional echocardiography is useful for the immediate diagnosis of acute myocardial infarction when diagnostic electrocardiographic changes are absent. The technique is also helpful in distinguishing myocardial infarction from other conditions that may clinically or electrocardiographically mimic infarction. Th...

journal_title：Mayo Clinic proceedings

authors： Oh JK,Miller FA,Shub C,Reeder GS,Tajik AJ

更新日期：1987-01-01 00:00:00

abstract：:Nasal telangiectasias, a common condition, can be caused by chronic exposure to ultraviolet light, rosacea, topically applied corticosteroids, or rhinoplasty. Use of the argon laser for 15 to 45 minutes in a continuous mode over the entire involved area can produce considerable lightening of the nasal redness and impr...

journal_title：Mayo Clinic proceedings

authors： Dicken CH

更新日期：1986-11-01 00:00:00

abstract：:We describe two patients with diffuse non-Hodgkin's lymphoma, hypercalcemia, and increased activity of serum angiotensin-converting enzyme. A mechanism similar to that operative in sarcoidosis is speculated to have caused the hypercalcemia. A lymphokine elaborated by the malignant lymphoma may cause activated macropha...

journal_title：Mayo Clinic proceedings

authors： DeRemee RA,Banks PM

更新日期：1986-09-01 00:00:00

abstract：:Dissatisfaction with the long-term results of cutaneous urinary diversion and a demand for a more socially acceptable solution have prompted the development of procedures that allow continent urinary diversion. Creation of an internal reservoir from reconstructed bowel segments, which is anastomosed to the patient's u...

journal_title：Mayo Clinic proceedings

authors： Goldwasser B,Barrett DM,Benson RC Jr

更新日期：1986-08-01 00:00:00

abstract：:Since 1980, impressive progress in the treatment of solid tumors has altered the practice of pediatric surgical oncology. Because these advances have been balanced by both liberal and conservative viewpoints, an accurate reassessment of traditional approaches has been possible. Noteworthy alterations in chemotherapy, ...

journal_title：Mayo Clinic proceedings

authors： Kaufman BH

更新日期：1986-04-01 00:00:00

abstract：:The surgical treatment of Crohn's disease is necessitated by complications of the disease or by failure of medical therapy. Despite the fact that the patients with Crohn's disease who undergo operation have the most severe spectrum of problems, about half these patients may never need a further procedure, and the mort...

journal_title：Mayo Clinic proceedings

authors： Wolff BG

更新日期：1986-04-01 00:00:00

abstract：:Although measurements of trunk flexibility are an important part of a clinical examination, subjective methods are usually used to assess spinal mobility. We studied three easily performed objective techniques for determining trunk flexibility (the common "fingertip-to-floor" test, the modified Schober and Moll tests,...

journal_title：Mayo Clinic proceedings

authors： Merritt JL,McLean TJ,Erickson RP,Offord KP

更新日期：1986-03-01 00:00:00

abstract：:A 36-year-old man sought medical attention because of pressure in his head and distention of the veins in his neck. Physical examination disclosed a murmur of aortic insufficiency, and a chest roentgenogram showed a dilated ascending aorta. Two-dimensional echocardiography and angiography demonstrated a large intimal ...

journal_title：Mayo Clinic proceedings

authors： Cooke JP,Safford RE

更新日期：1986-02-01 00:00:00

abstract：:The issue of whether patients who have invasive carcinoma in an otherwise benign polyp should undergo surgical resection of that bowel segment is controversial. We examined the records of 83 patients with such polyps that were removed endoscopically between 1978 and 1981. After exclusion of 18 patients from the study ...

journal_title：Mayo Clinic proceedings

authors： Fucini C,Wolff BG,Spencer RJ

更新日期：1986-02-01 00:00:00

abstract：:During the period November 1979 to October 1984, 19 patients at our institution underwent balloon angioplasty of partial or complete obstruction of aortocoronary artery saphenous vein bypass grafts. The procedures were performed a mean of 38 months after a coronary bypass operation to relieve recurrent angina of at le...

journal_title：Mayo Clinic proceedings

authors： Reeder GS,Bresnahan JF,Holmes DR Jr,Mock MB,Orszulak TA,Smith HC,Vlietstra RE

更新日期：1986-01-01 00:00:00

abstract：:Many misconceptions continue to persist in both the lay and the professional literature regarding the proper approach to the diagnosis and treatment of hypoglycemia. Often, patients with a symptom complex suggestive of hypoglycemia have normal levels of plasma glucose in association with these symptoms. The major diag...

journal_title：Mayo Clinic proceedings

authors： Nelson RL

更新日期：1985-12-01 00:00:00

abstract：:Patients with ectatic coronary arteries often have occlusion of the affected arteries. Because ectatic arteries are considered to have medial damage, they are normally assumed to have little capacity to constrict; therefore, spasm has not been considered a factor in the occlusive process. In two patients who had diffu...

journal_title：Mayo Clinic proceedings

authors： Bove AA,Vlietstra RE

更新日期：1985-12-01 00:00:00

abstract：:Duodenal duplication cysts are rare malformations that characteristically manifest with intestinal obstruction. In a 50-year experience, we found a duodenal duplication cyst in only three patients, one of whom had massive gastrointestinal bleeding as the initial symptom. Six other duplication cysts (two esophageal, on...

journal_title：Mayo Clinic proceedings

authors： Knight CD Jr,Allen MJ,Nagorney DM,Wold LE,DiMagno EP

更新日期：1985-11-01 00:00:00

abstract：:Essential blepharospasm is a progressive, bilateral, involuntary facial spasm. In this study, we conducted a prospective analysis of myectomy for the treatment of this condition in 21 patients. The procedure consisted of extirpation of the muscles that close the eyelids (protractors), which include the pretarsal, pres...

journal_title：Mayo Clinic proceedings

authors： Jones TW Jr,Waller RR,Samples JR

更新日期：1985-10-01 00:00:00